Profound thrombocytopenia and generalized hyperpigmentation following pyrimethamine use

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dc.contributor.authorSenanayake, M. P.
dc.contributor.authorMettananda, D. S. G.
dc.contributor.authorVidyatilake, Sudharma
dc.date.accessioned2021-09-23T05:29:17Z
dc.date.available2021-09-23T05:29:17Z
dc.date.issued2011
dc.description.abstractPyrimethamine is an effective anti-parasitic medication with a narrow therapeutic index. We report a child with toxoplasmosis who developed hyperpigmentation and profound thrombocytopenia during a course of treatment with pyrimethamine. These two unusual complications occurred in addition to folate deficiency and megaloblastic anaemia which are recognized adverse effects of this medication.
dc.description.abstractPyrimethamine is an effective anti-parasitic medication with a narrow therapeutic index. We report a child with toxoplasmosis who developed hyperpigmentation and profound thrombocytopenia during a course of treatment with pyrimethamine. These two unusual complications occurred in addition to folate deficiency and megaloblastic anaemia which are recognized adverse effects of this medication
dc.identifier.citationSenanayake, M. P., Mettananda, D. S. G., & Vidyatilake, S. (2011). Profound thrombocytopenia and generalized hyperpigmentation following pyrimethamine use. Sri Lanka Journal of Child Health, 40, 134-135.en_US
dc.identifier.urihttp://archive.cmb.ac.lk/handle/70130/6043
dc.language.isoenen_US
dc.publisherSri Lanka college of pediatriciansen_US
dc.subjectPyrimethamineen_US
dc.subjectprofound thrombocytopeniaen_US
dc.subjecthyperpigmentationen_US
dc.titleProfound thrombocytopenia and generalized hyperpigmentation following pyrimethamine useen_US
dc.typeArticleen_US

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