A pilot study on comparison of rapid immunodiagnostics for leptospirosis infections

Abstract

In Sri Lanka, leptospirosis is mostly diagnosed on clinical grounds. Serological confirmation is not obtainable during the acute stage of the illness. There is a need for rapid immunodiagnostics for confirmation of leptospirosis. Two immunodiagnostic assays, ie enzyme linked immnnosorbent assay (ELISA) and immunochromatographic technique-Leptocheck-WB test (LCT) are used to detect leptospira specific IgM antibodies which are prevalent in the early stages of acute infections.