The Effect of Pyospermia on Male Infertility

Abstract

A cross sectional study was carried out on written consent in a fertility clinic of Sri Lanka during the period of August 2014 to August 2017 to find out the relationship of pyospermia with seminal parameters such as seminal volume, count, mortality and morphology. The amount of 105 subjects who had fertility issues were screened for seminal analysis (pus cells were counted separately with Giemsa staining technique) and found to have 40 of them were pyospermic (over 5 seminal pus cells per high power field/HPF). Out of them 15 were having over 10 seminal pus cells per HPF. The seminal parameters of Indnivuals with pus cells (5-10 /HPF) were compared with that of control group and found to have no statistical significance between the two groups. Anyway a dramatically negative relationship was found between pyospermia (over 10 pus cells / HPF) and seminal parameters such as motility and morphology. This could be due to the secretary materials of pus cells (harmful to sperms) such as collagenase, reactive oxygen species which are proportionate to the number of pus cells found in the semen. Thus, it is important to suppress the pyospermia condition especially with over 10 pus cells/HPF in the management of male infertility