Serum anti-oxidant capacity and NOx levels in leptopsirosis patients

Abstract

Release of reactive oxygen and reactive nitrogen species (ROS and RNS) contribute to increased oxidative stress and also tissues damage which is thought to lead to multi-organ failure in Leptospirosis. The antioxidant capacity (AOC) of serum provides a measure of overall protection against oxidative damage. RNS (ie., nitric oxide (NO ) released is immediately converted to NO2 and NO3 (NOx) and serum NOx levels reflect the level of NO released.