A critical review of pharmacodynamics properties of ingredients of Patola vishvadi kashaya for treating Amlapitta (Gastritis)

Abstract

Gastritis is an inflammatory disease of the gastric mucosa. According to the World Health Organization, the global prevalence of gastritis was around 1.8-2.1 million cases annually in 2012. In Ayurveda, gastritis can be correlated with Amlapitta, which is caused by vitiated Agni and Pachakapitta. This high prevalence underscores the need to explore diverse treatment options, including traditional remedies like Ayurveda decoctions. This study aims to critically review the pharmacodynamics properties of the ingredients in Patola vishvadi kashaya, focusing on their effects on Amlapitta. The medicinal prescription was selected from Cakradatta, Chikithsa Sangraha, and pharmacodynamics properties collected from authentic texts, previous research, journal articles, and websites. The ingredients include Dummella (Tricosanthus cucumerina), Dry Ginger (Zingiber officinale), Rasakinda (Tinospora cordifolia), and Katukarosana (Picrohiza kurroa). The Rasa of Kashaya contains 50% Tikta, 33% Katu, and 17% Kashaya. Among the Guna, 50% are Laghu, 38% Ruksha, and 12% Snigdha. Additionally, 75% of the drugs have Ushna Veerya, while 25% have Sheetha Veerya.