Cellular Immune Responses to Plasmodium Vivax Malaria
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Faculty of Medicine: University of Colombo
Abstract
Human cellular responses to plasmodium vivax blood stage antigens were studied.
Two catagories of malaria convalescents - individuals resident in a malaria
non-endemic region and individuals resident in a malaria endemic area were
included. The cellular responses assayed were proliferatio and IFN gamma
production by peripheral mononuclear cells in response to a soluble extract of
P.vivax blood stage antigen, to two cloned P.vivax antigens GAM - 1 and PV 200
used as bacterial fusion proteins, a non malarial antigen PPD and to a mitogen
Description
A thesis submitted for the Degree of Doctor of Philosophy of the University of Colombo (Faculty of Medicine)
Keywords
Malaria, Vivax, Malaria, Vivax-Immunology