Use of clonidine-naltrexone for rapid withdrawal in two patients dependent on intravenous morphine

Abstract

There are no published reports of intravenous morphine abuse in Sri Lanka. We describe the use of rapid detoxification using clonidine and naltrexone in two patients dependent on intravenous morphine. There were minimal withdrawal effects and no serious adverse events during the withdrawal period. Both patients remain abstinent one month after completing the rapid withdrawal.