Standardization and Evaluation of Jatamamshadi Syrup Panaka in The Management of Anidra (Insomnia)

Abstract

Jaṭamaṃshadi Syrup Panaka is a traditional Ayurvedic formulation mentioned in the Deshiya Chikitsa Sangrahaya. It contains Jaṭamaṃsi (Nardostachys jatamansi), Ela (Elettaria cardamom), and Maricha (Piper nigrum Linn.), and is traditionally used for the management of Anidra (insomnia). The objectives of the study are to evaluate its therapeutic effect on insomnia, along with its physicochemical parameters, phytochemical constituents, and shelf life. The syrup was prepared, and phytochemical screening, physicochemical evaluations and organoleptic evaluation were carried out at the Department of Dravyaguna Vignana, University of Colombo. Thin Layer Chromatography (TLC) was performed at the Industrial Technology Institute, Colombo. An observational case study was conducted at the Professorial Unit, Department of Kayachikitsa, Ayurveda National Teaching Hospital. A patient aged between 20–75 years, with a history of insomnia for less than two years, was selected. Patients with pregnancy, allergies, or pain disorders were excluded. The patient administered 30 ml of the syrup daily at 9:00 p.m. for two weeks, followed by a two-week observation period. Sleep quality was assessed using the Pittsburgh Sleep Quality Index. Post-treatment results indicated a 56% reduction in sleep disturbances and improvements in physical (33%), mental (31%), social (33%), and overall quality of life (44%). Phytochemical analysis confirmed the presence of alkaloids, flavonoids, saponins, carbohydrates, terpenoids, and glycosides. The syrup had a pH of 3.73, refractive index of 1.065, and density of 1.0209 g/ml. The findings suggest that Jaṭamaṃsadi Syrup Panaka may effectively improve sleep quality. Further studies of larger sample sizes are recommended.