Malaria Vaccine Studies on Anopheles Midgut Glycoproteins and a Plasmodium Falciparum Merozoite Surface Protein

Abstract

Vaccination is an alternative approach to control malaria because of the development of insecticide resistance in mosquito vectors and drug resistance in parasites. In this context, two different approaches viz, transmission blocking, using mosquito midgut (MG) glycoproteins, and eliciting immunity to asexual stage parasite antigens, using Plasmodium falciparum merozoite surface antigen 2 (PfMSA2) were investigated.