Analyzing the efficacy of Amritadya Guggulu and Bhramaree Pranayama on hyperlipidemia

Abstract

Disproportionately high lipid concentration in blood is a characteristic of hyperlipidemia which is mentioned as Medo Roga in Ayurveda. Physiological stress is a cause of hyperlipidemia and Bhramari Pranayama produces a relaxed state of mind. Hyperlipidemia increases a person's risk of developing hypertension. The objective of this study was to analyze the efficacy of Amritadya Guggulu (AG) and practice of Bhramaree Pranayama in hyperlipidemic patients. Study was a randomized, clinical study with 8-week treatment and 3 month follow up periods. Ethical clearance was obtained from the Institute of Indigenous Medicine, University of Colombo. Total of forty-four hyperlipidemic patients with total cholesterol (TC) >240 mg/dL, of both genders, aged between 30 to 79 years, were randomly selected from outdoor patient department of Swastavritta clinic, National Ayurveda Teaching Hospital, Borella. Selected patients were treated with AG powder and practice of Bhramaree Pranayama. All the symptoms showed improvement (p<0.05), indicating strong statistical evidence of improvement. Thirst, hunger, hyperhidrosis, body odour, body strength, sexual performance and breathing difficulty all have p-values <0.001, showing highly significant improvements. There was significant reduction in TC (p<0.01), LDL (p<0.05) and Risk Ratio (p<0.05) and VLDL (p<0.05) after the treatment. Statistically significant reduction in Body Mass Index (BMI) (p<0.01), weight (p<0.01), systolic blood pressure (p<0.01), diastolic blood pressure (p<0.05) were observed after the treatment. After the treatment kidney function (SGOT, SGPT), serum creatinine, GFR did not show a significant change (p>0.05). Present study concluded that Amrithadya Guggulu and Bhramaree Pranayama were significantly effective in treating hypolipidemia