Abstract:
Complete paralysis of one half of the body called hemiplegia . Stroke is the major
consequence of cerebrovascular disease, known as second most common cause of death.
Annually, 15 million people worldwide suffer from strokes. Hemiplegia is a condition
similarto Pakshaghata. It is one of the Vata Vyadhis. In Ayurveda Nidana Parivarjana,
Shodana and Shamana Chikitsa used for treatment line of Pakshaghata.Denibadiya
decoction commonly used in traditional system of medicine in Sri Lanka for
Pakshaghata.Objectives were, to find out most commonly used decoction in treatment line
for Pakshaghata, and to study pharmaceutical analysis of selected decoction.Denibadiya
decoction is identified as most commonly used decoctionin survey in Ayurveda teaching
Hospital, Borella. According to survey, total 21 types of preparation of drugs used as
treatment line of Pakshaghata within 8 weeks. In those preparations; 4 types of Kashaya
(19.04%), 3 types of Vati (14.28%), 2 types of Kalka(09.52%), 5 types of Taila (23.80%), 1
type of Leha (04.76%), 1 type of Pattu/Mallum/Plaster (04.76% ) , and 5 types ofChoorna
(23.80%) were identified as treatment line. Among the used 4 types of Kashaya the most
importantlyDenibadiya used during 6 weeks. Pharmaceutical analysiscompleted for 8 types
of ingredients of Denibadiya decoction in DravyagunaVignana Laboratory of Institute of
Indigenous Medicine, University of Colombo. According to physical and chemical analysis
of 8 types of ingredients of Denibadiya decoction, it can be concluded as observed physical
analysis, Foreign matter value (1.58%), Color (brownish red), Odor (pungent), Taste (
Thiktha and Kashaya ), PH value (6.19 ), Moisture content ( 15.44% ), Total ash value
(9.025%),Water soluble ash content (6.45%), Acid insoluble ash content (17.75%).
According to the observed chemical analysis, Flavonoids, Saponins, Terpenoids, Alkaloids,
Glycosides, Carbohydrates, Tannins, Proteins were present except Steroids. Results of Thin
Layer Chromatography was done (Rf1- 9.6, Rf2-1.4,Rf3 1.04). It could be recommended that
statistical analysis of revealed data and efficacy of Denibadiya decoction will be evaluated in
further clinical study for treatment according to progress of the patients of Pakshaghataas
continuation of this study.
