Abstract:
Sri Lankan Ayurveda clinical practice Satapushpa Shatavari powder
(SSP) with or without Satapushpa Shatavari Grita (SSG) enema is used for manage
menstrual disturbances due to polycystic ovary syndrome (PCOS). Objective of
Present study was to evaluate the efficacy of Satapushpa Shatavari Churna with
Satapushpa Shatavari Grita Matra Vasti for the management of PCOS by an open
label comparative clinical trial. Successful screening 60 PCOS participants were
randomly divided into three groups (n = 20) viz Group A (Oral Administration of
SSP 05g t. d. s. with 10 ml of cows ghee for 2 weeks), Group B (Rectal
Administration of SSG as enema, 60 ml / day for 2 weeks with 1 week gap) and
Group C (oral and rectal administration of SSP and SSG drugs respectively). After
one month administration period participants in group A, B and C were assessed on
PCOS appearance of the ovary, volume of the ovary, endometrial thickness by US
scan. Further volume of menstrual flow, intermenstrual period and hirsutisum was
assessed by standard scoring system. The study revealed that all treated groups were
reduced their ovarian volumes when compare with pretreated stages. Endometrial
thickness of each groups were improved and group C was shown significant
improvement. Hirsutisum ratings score was significantly improved in group C.
Quantities of the menstruation of all drug treated groups were significantly
improved. The findings of the present study indicate that SSP therapy leads to
comparable reduction of ovarian volume in a manner, which correlates with the
degree of reduction of PCOS and related signs.
