Abstract:
Background: Antibiotic resistance is a worldwide emergency with a substantial healthcare and economic
burden resulting in multi-drug resistant infections. Knowledge, attitude and practices of healthcare
undergraduates can significantly influence antibiotic use as future healthcare professionals.
Objective: To study Knowledge, Attitude, and Practices (KAP) of Self-Medication of Antibiotics (SMA)
among medical and nursing undergraduates of the University of Colombo, Sri Lanka.
Methods: A descriptive cross-sectional study was conducted from March 2022 to January 2023 among 401
nursing and medical undergraduates. Data was collected using a pre-designed self-administered
questionnaire and was analyzed using SPSS version 26. A significant level was set as p<0.05 and results
were presented in terms of descriptive statistics. Associations between demographics and KAP were
defined in terms of Pearson’s chi-squared test. Mean comparisons of KAP between two faculties were
performed using an independent sample t-test.
Results: The study participants have a female majority (62.30%) aged 23-26 years (63.10%). Among the
study subjects, only 19.10% of medical undergraduates and 23.30% of nursing undergraduates have good
knowledge of SMA with a mean score of 9.79 (SD =2.10). Most participants (64.80%) have positive
attitudes with a mean score of 7.71 (SD=1.69) and 64.58% have good practices toward SMA with a mean
score of 8.45 (SD=2.28). Statistically significant associations were found between knowledge and the
academic year (p=0.001) and age groups (p<0.001). Moreover, 46.1% have self-medicated themselves
within the last year whereas Amoxicillin (15%) has the highest frequency. A significant association was
identified between knowledge and practice of SMA (p<0.001) and between attitude and practice of SMA
(p<0.001).
Conclusion: Results showed that participants with good knowledge have significantly good practices of
SMA. Participants with positive attitudes tend to follow good practices related to SMA. Despite having a
good knowledge of antibiotics, the majority of the undergraduates have an average attitude regarding SMA
which is not satisfactory in a healthcare-related undergraduate population.
