Allelic polymorphisms of Malarial and human genes in relation to disease occurrence and pathogenesis

Perera, W. V. J.

dc.contributor.author	Perera, W. V. J.
dc.date.accessioned	2022-03-28T05:15:04Z
dc.date.available	2022-03-28T05:15:04Z
dc.date.issued	1999
dc.identifier.citation	Faculty of medicine, University of Colombo, 1999 Degree : Ph. D	en_US
dc.identifier.uri	http://archive.cmb.ac.lk:8080/xmlui/handle/70130/6530
dc.description	Faculty of Medicine, University of Colombo, 1999 Degree : Ph. D	en_US
dc.description.abstract	Among the determinants of pathogenesis of malarial disease, parasite genetic factors and host genetics play a major role. Human TNF allele polymorphisms and their associations with severe infectious diseases and genetic composition of malarial infections were studied using PCR oligonucleotide probing. The results of this study showed that the mean number of genetically distinct parasite clones per isolate for parasite infections in Kataragama (endemic) patient population (2.17) is significantly higher than the parasite isolates from patients in Colombo (non endemic) (1.59=0.0001)	en_US
dc.language.iso	en	en_US
dc.publisher	University of Colombo	en_US
dc.subject	Malaria-genetics	en_US
dc.title	Allelic polymorphisms of Malarial and human genes in relation to disease occurrence and pathogenesis	en_US
dc.type	Thesis	en_US