Profound thrombocytopenia and generalized hyperpigmentation following pyrimethamine use

Senanayake, M. P.; Mettananda, D. S. G.; Vidyatilake, Sudharma

dc.contributor.author	Senanayake, M. P.
dc.contributor.author	Mettananda, D. S. G.
dc.contributor.author	Vidyatilake, Sudharma
dc.date.accessioned	2021-09-23T05:29:17Z
dc.date.available	2021-09-23T05:29:17Z
dc.date.issued	2011
dc.identifier.citation	Senanayake, M. P., Mettananda, D. S. G., & Vidyatilake, S. (2011). Profound thrombocytopenia and generalized hyperpigmentation following pyrimethamine use. Sri Lanka Journal of Child Health, 40, 134-135.	en_US
dc.identifier.uri	http://archive.cmb.ac.lk:8080/xmlui/handle/70130/6043
dc.description.abstract	Pyrimethamine is an effective anti-parasitic medication with a narrow therapeutic index. We report a child with toxoplasmosis who developed hyperpigmentation and profound thrombocytopenia during a course of treatment with pyrimethamine. These two unusual complications occurred in addition to folate deficiency and megaloblastic anaemia which are recognized adverse effects of this medication.
dc.description.abstract	Pyrimethamine is an effective anti-parasitic medication with a narrow therapeutic index. We report a child with toxoplasmosis who developed hyperpigmentation and profound thrombocytopenia during a course of treatment with pyrimethamine. These two unusual complications occurred in addition to folate deficiency and megaloblastic anaemia which are recognized adverse effects of this medication
dc.language.iso	en	en_US
dc.publisher	Sri Lanka college of pediatricians	en_US
dc.subject	Pyrimethamine	en_US
dc.subject	profound thrombocytopenia	en_US
dc.subject	hyperpigmentation	en_US
dc.title	Profound thrombocytopenia and generalized hyperpigmentation following pyrimethamine use	en_US
dc.type	Article	en_US