Abstract:
Hyperlipidemia is a risk factor for cardiovascular mortality, an
important cause of death after renal transplantation. We studied the serum lipid
profiles of 34 patients aged 18 to 58yrs (mean 36.6±11.5) 6 to 50 months after the
transplantation. The lipid profiles were measured after a 14h fast. The results are
as follows:- Serum total cholesretrol (CHOL): 218.21±53.47, serum triglyserides
(STG): 145.21±51.0,HDL-cholesterol (HDL-C):49.35±9.37,LDLcholesterol(LDL-C): 141.88±49.57, Total cholesterol, HDL- cholesterol
ratio:4.53±1.04. The following observations were made when these results were
compared with the lipid values of a local reference population group. No
significant differences in the Total CHOL, LDL-C, and the total CHOL, HDL-C
ratio were found between the two groups. The transplant patient group showed
higher HDL-C and STG levels. The favourable trend in the lipid status observed
in this group of transplant patients was in contrast to previously reported
observations. This might be due to the fact that our patients are treated with low
doses of cyclosporine and steroids. However a long observation period in a large
number of patients is required before final conclusions could be drawn.
