Abstract:
Introduction: Use of donor sperm for intra
uterine insemination in the treatment of severe
male factor infertility is a common treatment
modality. However sperm banking and donor
sperm insemination is relatively new to Sri
Lanka. Moreover base line data on seminal
parameters of healthy volunteers are not available
in the country.
Objectives: To evaluate the status of donor sperm
parameters and the results of donor sperm
insemination at a recently established sperm bank
in Sri Lanka.
Methodology: Data from the records (n=96) of
the sperm donor programme and results 120
donor insemination treatment cycles in 52
recipient couples using frozen semen samples of 29
donors were analysed. The mean treatment cycles per sperm donor were 4.1.
Results: Of the 96 men volunteered to donate
semen, only 43.7 %( n= 42) had all the sperm
parameters within normal limits as per WH O criteria. In 46.3% cases either a single or a
combination of sperm abnormalities were found.
T wo volunteers were azoospermic .
Oligozoospermia was found in 10.4% (n—10),
asthenozoospermia in 49.5% (n = 46) and
teratozoospermia in 19.8 %(n=16). Of the
recipient couples (n=52), mean duration ot
infertility was 4.9 (range 3-14) years and mean age
of the female partners was 33.3 (range 20-41)
years. Among the male partners of recipient
couples, 76.5% (n=40) had azoospermia. 5.9%
(n=3) had aspermia and 17.6% (n = 9) had severe
oligoasthenoteratozoospermia. The success rate
of the sperm donor programme as per recorded
data was 31.4% (n=16) per couple and 13.3% per
treatment cycle. The highest success rate was
observed in the first attempt while the cumulative
rate increased up to the 4''' attempt. A higher
percentage of the pregnant women were less than
30 years of age.
Conclusions: In Healthy men volunteering to
donate sperm the prevalence of sperm
abnormalities is high, the commonest abnormality
is asthenozoospermia. The success rate of the
sperm donor programme is 31.4 % per couple and
13.3% per treatment cycle. The highest success
rate was at the first attempt while the cumulative
rate increases up to the 4''' attempt. As in all
infertility treatment procedures, the age of the
female is a critical factor in the success of donor
insemination.
