Abstract:
Abstract: Objectives: To evaluate diabetes related complications with sociodemographic factors.To assess the effect of family history of diabetes in terms of
age of onset of disease. Methods: Data obtained from a consecutive sample of
diabetic patients with an age of onset of disease <40 years (n=1007). Recruitment
was through both governmental and private hospital outpatient clinics. Informed
written consent was obtained. Data collected on socio-demographic variables as
well as end-organ complications. After enrollment basic demographic data, family
history of diabetes, hypertension, ischaemic heart disease, stroke, deafness and
age at diagnosis were obtained. Analysis done by SPSS 17.0 with use of
descriptive analysis of variance and logistic regression models. Results:
Prevalence of major complications were as, retinopathy (15.6%), neuropathy
(3.5%), nephropathy (32.5%), foot ulceration (10.1%), ischaemic heart disease
(23%) and peripheral arterial disease (6.9%). The socio-demographic model
significantly correlated with most of the above complications (p<0.05). Age was
the single demographic determinant having independent positive correlation on all
of above outcomes (p <0.05). 741(73.58%) patients had a close family history of
diabetes. Most prevalent was history of diabetes in the mother (n=435; 43.2%).
Overall family history was significantly associated with age of onset of diabetes (p
<0.05).Conclusion: Socio-demographic model is effective in predicting outcome
of diabetes. Family history of diabetes is significantly correlated with age of onset
of disease in young diabetic patients.
