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Now showing items 1-20 of 48

Effect of Karawila (Momordica Charantia) on the glucose tolerance in maturity onset diabetes

Welihinda, J.; Karunanayake, E. H.; Jayasinghe, K. S. A.; Sheriff, M.H.R. (1983)

The hypoglycaemic action of the fresh juice of the dried extract of the fruit of Momordica charantia (Karawila) has been reported both in laboratory animals and during clinical trials with diabetic patients. Phytochemical ...
The value of the use of renal function indices in distinguishing prerenal failure from established acute oliguric renal failure

Gunathilake, N.; De Mel, T.; De Mel, W.C.P.; Sheriff, M.H.R.; Dharmadasa, K. (1987)

Abstract :In a search for simple and reliable measurements to evaluate the common clinical dilemma of acute oliguric renal failure, 35 patients admitted to the University Medical Unit, Colombo, were prospectively studied. ...
Preliminary analysis of lipid status in kidney transplant patients

Anapalahan, M.; Dhammika Menike, A.M.S.; Nanayakkara, S.; Jayasinghe, S.; Sheriffdeen, A.H.; Sheriff, M.H.R. (Sri Lanka Medical Association, 1991)

Hyperlipidemia is a risk factor for cardiovascular mortality, an important cause of death after renal transplantation. We studied the serum lipid profiles of 34 patients aged 18 to 58yrs (mean 36.6±11.5) 6 to 50 months ...
Use of international non-proprietary nomenclature (INN) and proprietary terms for drugs in general Hospital, Colombo (GHC)

Kuruppuarachchi, L.; Jayasinghe, K.S.A.; Sheriff, M.H.R. (Sri Lanka Medical Association, 1992)

Mandatory use of INN (or generic names) when prescribing is controvelsial. Nevertheless, use of INN for state sector should be less controversial, because only the most cost-effective preparations obtained via the State ...
Atypical presentation of malaria in Sri Lanka associated with chloroquine resistance

Alles, H.K.; De Silva, D.; Naotunna, T.D.S.; Pathirana, P.P.S.L.; Jayasinghe, S.; sheriff, M.H.R.; Mendis, K.N. (1994)

Abstract : The classical clinical picture of malaria is one of paroxysmal fever with chills arid rigors. However in the recent past we have encountered an increasing number of Plasmodium falciparum patients with a widely ...
Safety in humans on the use of combinations of albendazole with ivermectin or diethylcarbamazine (DEC)

Ismail, M. M.; Jayakody, L.; Nirmalan, N.; Jayasinghe, S.; Rajaratnam, H. N.; Perera, C.S.; Amarasekera, N.; Sheriff, M.H.R. (1994)

Both DEC and ivermectin have been shown to have microfilaricidal activity against Wuchereria bancrofti. Recent studies have shown albendazole to have a filaricidal activity as well. It was considered useful to determine ...
Urinary N-acetyl-beta-D glucosaminidase (uNAG) as an index of renal damage: a preliminary study

De Silva, A.; Ariaratnam, C.A.; Chandrasekharan, N.V.; Karunanayake, E.H.; Sheriff, M.H.R. (1994)

Abstract :The importance of the measurement of uNAG for the early detection of renal damage, was apparent from studies reported in literature. Prior to the present study, urinary enzymes including NAG have not been used ...
Plasmodium vivax malaria: Is it still benign?

Alles, H.K.; Gunawardana, N.; Kularatne, S.A.M.; Arambepola, M.; Sheriff, M.H.R.; Carter, C.; Jayasinghe, S.; Mendis, K.N. (1996)

200 malaria patients were assessed in a prospective hospital-based project in Anuradhapura and Colombo, to study severe and complicated infections. Malaria was diagnosed either on microscopy or PCR. Severe and complicated ...
The use of low molecular weight heparin (LMWH) in haemodialysis (HD)

Indrakumar, J.; Mujahieth, M. I.; Rajapakse, S.; Ransi, W.; Premaratne, G. M.; sheriff, M. H. R. (1996)

Abstract : Introduction: Unfractionated heparin (UFH) which is widely used as an anti coagulant in haemodialysis cannot be regarded as an ideal anticoagulant since its use is associated with increased post HD bleeding ...
Nebulization: is it done properly? A clinical audit

Kudalugoda Arachchi, J.; Fernando, S.S.D.; Sheriff, M.H.R. (1999)

To audit the current clinical practice and the level of understanding on nebulizer therapy. Setting: General medical wards, the Medical Intensive Care Unit (MICU), and emergency care unit (ETU) of the National Hospital of ...
Descriptive study of SLE patients followed up in the University of Colombo Lupus Research Clinic

Galappatthy, P.; Wazeel, A.N.; Kudalugoda Arachchi, J.; Mezamia, N.; Fernando, S.S.D.; Sheriff, M.H.R. (1999)

The university lupus research clinic follows up patients admitted or referred to the University Medical Unit with diagnosed or suspected SLE.Objectives: To find the number of patients in the lupus clinic with confirmed ...
Incidence of cough with angiotensin converting enzyme inhibitors in Sri Lankan population

Hewamanne, B.S.L.; Constantine, G.R.; Liyanarachchi, T.; Rajapakse, S.; Sheriff, M.H.R. (2000)

Abstract : Introduction: Angiotensin Converting Enzyme Inhibitors (ACEI) are widely used in clinical practice. Their use is often limited by cough. The incidence of cough among patients taking ACEls varies widely. The ...
ABNORMAL GLUCOSE TOLERANCE AND THE FETO-MATERNAL OUTCOME

Kaluarachchi, A; DeAlwis, D; Gnanasekeream, R; Gunawdnsa, N; Wijeratne, C N; Seneviratne, H R (2001)

Objective: To determine the maternal/ fetal outcome of abnormal glucose tolerance in pregnancy. Setting : The University Obstetric Unit, De Soysa Hospital for Women, Colombo. Design : A retrospective descriptive ...
Management of occupational exposure to blood and body fluids among health care workers in the National Hospital of Sri Lanka: an audit of practice

Vithana, V. H.; Weerakkody, M. I.; Pallewela, V. H.; Karunanayake, P.; Senarath, U.; sheriff, M. H. R. (2005)

Abstract : Background: Occupational exposure to blood-borne viruses is an important issue for health care workers (HCWs). Guidelines for their management are known to be implemented sub optimally. Objectives: To assess ...
Retinopathy among young adult diabetic subjects - preliminary data from the Sri Lanka young diabetes study

Katulanda, P.; Mahesh, J. G.; Wljesinghe, N. P.; Silva, M. A. U.; Asfir, E. L.; sheriff, M. H. R. (2006)

Diabetes mellitus can lead to sight threatening retinopathy. Blindness can be prevented by early detection and effective intervention. Objective: To determine the prevalence of retinopathy among young adult diabetic ...
High prevalence of diabetes dyslipidaemia among young adult onset diabetes subjects in Sri Lanka.

Katulanda, P.; Silva, A.; Wijeyaratne, S. M.; Shine, B.; Matthews, D. R.; sheriff, M. H. R. (2007)

Abstract : Objectives: South Asians are at increased risk of diabetes and cardiovascular disease (CVD).We aimed to identify the prevalence and patterns of dyslipidaemias among subjects with young adult diabetes in Sri ...
Metabolic syndrome among adults in Sri Lanka- urbanization snd sedentary lifestyles driving the epidemic

Katulanda, P.; Perera, G. L. R. S.; Karunaratne, K. G. N. S.; Constantine, G. R.; Matthews, D. R.; sheriff, M. H. R. (2007)

Abstract : Background: Metabolic syndrome has been defined as an entity with clustering of cardiovascular risk factors. There was no countrywide data on metabolic syndrome for Sri Lanka. We aimed to determine the prevalence ...
Smoking among adults in Sri Lanka -Facts and figures

Wickramasinghe, W. A. K. K.; Karunaratne, K. G. N. S.; Perera, G. L. R. S.; Ganegoda, U. A.; Silva, A.; Katulanda, P.; Constantine, G. R. (2007)

Abstract : Objectives: To determine the prevalence and patterns of smoking among different socio-demographic groups in Sri Lanka. Methodology: A nationally representative cross sectional study was conducted in 7 out ...
Diabetes due to the mt3243 A>G mutation among young adult diabetic subjects in Sri Lanka - prevalence and clinical heterogeneity

Katulanda, P.; Silva, A.; Mahesh, J. G.; Sheriff, M.H.R.; Matthews, D. R.; McCarthy, M. I.; Gloyn, A. L. (2007)

The maternally inherited mt3243A>G mutation is associated with a variable clinical phenotype including diabetes and deafness (MIDD). The frequency of this mutation in Sri Lanka (SL) is not known. We aimed to determine the ...
Prevalence and phenotype characterstics of latent autoimmune diabetes in adulthood (LADA) and type 1 diabetes among young adults in Sri Lanka

Katulanda, P.; Shine, B.; Katulanda, G. W.; Mahesh, J. G.; Silva, A.; Ganegoda, U. A.; Sheriff, M.H.R.; Somasundaram, N.; Wijesuriya, M.; Matthews, D. R. (2008)

Abstract: Background: Sri Lankans are at high risk of diabetes. Knowledge of the aetiology is useful in disease prevention. Objectives: To determine the prevalence and clinico-metabolic characteristics of Glutamic Acid ...

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