Abstract:
This retrospective analytical study aimed at making a database of patients who
underwent renal transplant from 31 December 2004 to 31 December 2006 under the
Faculty of Medicine renal transplant program. The objective was to build a
profile of renal transplant patients with focus on post KT infections and
complications of renal transplants. An interviewer administered questionnaire was
used. A total of 72 patients were studied; 18 (25%) had died by February 2007.
Forty-three patients (58.3%) were interviewed in person, 17 were interviewed over
the phone and 12 patients could not be contacted. Of those who were interviewed,
28 (38.9%) were on azathioprine, prednisolone and cyclosporine, while 15 (20.8%)
were on prednisolone, cyclosporin and mycophenolate mofetil. Four patients had
symptomatic cytomegalovirus infection and five had tuberculosis post transplant.
Of all infections, the most commonly reported was urinary tract infection (11
cases). Thirty-three (45.8 %) had received induction therapy with either
basiliximab (n = 8) or daclizumab (n = 25). Acute rejection was the most commonly
encountered complication, with nine cases (12.5%) being reported over the study
period. Of late complications, most were due to immunosuppression. Overall, the
2-year survival was 75%. There was no significant difference between the centers
of transplant.