Browsing Department of Statistics by Issue Date

Now showing items 1-20 of 103

SAMPLE SIZE REVIEW IN A HEAD INJURY TRIAL WITH ORDERED CATEGORICAL RESPONSES

Bolland, K.; Sooriyarachchi, M.R.; Whitehead, J. (Wiley, 1998)

Between 1993 and 1996, a total of 452 patients were entered into a randomized trial evaluating eliprodil (a non-competitive NMDA receptor antagonist) in patients suffering from severe head injury. The primary efficacy ...
A method for sequential analysis of survival data with non-proportional hazards.

Sooriyarachchi, M.R.; Whitehead, J (Wiley Blackwell, 1998)

Two tests are proposed for comparing the survival curves of patients randomised between an experimental treatment and a control treatment when it is anticipated that the two survival curves may not satisfy the assumption ...
Mid-trial design reviews for sequential clinical trials

Whitehead, J; Whitehead, A; Todd, S; Bolland, K.M.; Sooriyarachchi, M.R. (Wiley, 2001)

When sequential clinical trials are conducted by plotting a statistic measuring treatment di erence against another measuring information, power is guaranteed regardless of nuisance parameters. However, values need to ...
Generating Small Area Statistics for Household Income in Southern Province of Sri Lanka

Jayasekera, Anoma S.; Wickremasinghe, W.N. (2003)

Human development is a central objective of economic activity and forms the main purpose of social investment in any country. The Human Development Index (HDI) defined by the UNDP 1 is based on three dimensions: namely, ...
Incorporating data received after a sequential trial has stopped into the final analysis : implementation and comparison of methods

Sooriyarachchi, M.R.; Whitehead, J.; Bolland, K.M.; Whitehead, A.; Matushita, T. (Wiley Blackwell, 2003)

In a sequential clinical trial, accrual of data on patients often continues after the stopping criterion for the study has been met. This is termed “overrunning.”Ov errunning occurs mainly when the primary response from ...
A practical comparison of group-sequential and adaptive designs

Kelly, P; Sooriyarachchi, M.R.; Stallard, N.; Todd, S. (2005)

Sequential methods provide a formal framework by which clinical trial data can be monitored as they accumulate. The results from interim analyses can be used either to modify the design of the remainder of the trial or ...
The sequential analysis of binary responses: a score test for the case of three time points

Sooriyarachchi, M.R.; Whitehead, J.; Whitehead, A.; Bolland, K.M. (Wiley, 2005)

In this paper a robust method is developed for the analysis of data consisting of repeated binary observations taken at up to three xed time points on each subject. The primary objective is to compare outcomes at the ...
University selection among students of different streams : A comparison of methods’

Yatapana, P.S.; Sooriyarachchi, M.R. (2006)
Compliance for single and multiple dose regimes of superactivated charcoal: a prospective study of patients in a clinical trial

Mohamad, F.; Sooriyarachchi, M.R.; Senarathna, L.; Azhar, S.; Sheriff, M.H.R.; Buckley, N.A.; Eddleston, M. (2007)

Background. Although activated charcoal is widely used for the treatment of self-poisoning, its effectiveness is unknown. An important consideration is patient compliance since poor compliance will limit effectiveness. ...
Effectiveness of Using Quantified Intermarket Influence for Predicting Trading Signals of Stock Markets

Tilakaratne, Chandima D.; Mammadov, Musa A.; Morris, Sidney A. (2007)

This paper investigates the use of influence from foreign stock markets (intermarket influence) to predict the trading signals, buy, hold and sell, of the of a given stock market. Australian All Ordinary Index was ...
Log-linear models for ordinal multidimensional categorical data

Kuruppumullage, Prabhani; Sooriyarachchi, M.R. (2007)

This study emphasised on methods for analysis of categorical data having ordered categories for the multidimensional case and the paper discusses some of the specialized models which efficiently use the information on ...
.Failure time regression to determine warranty policies of computers

Dharmarathne, TMRT; Sooriyarachchi, M.R. (2007)

The present era of consumerism has substantially redefined the relationship of buyer and seller. Heightened consumer expectations have placed more responsibility on the manufacturer for the performance of his goods and ...
Design and analysis techniques for many-to-many matched case-control studies: An illustration using the Ille-et-Vilaine database for esophageal cancer

Kuruppumullage, P.; Sooriyarachchi, M.R. (2007)

Case-control studies, that investigate combinations of circumstances causing many diseases is largely in practice in many real world situations. Matching in case-control studies adjust for the effects of confounding variables ...
A Neural Network Approach For The Directional Prediction Of A Stock Market: An Application To The Australian All Ordinary Index

Tilakaratne, C. D. (2008)

This study investigates the capability of neural network-based approaches for predicting the direction (up or down) of a stock market. The Australian Stock market index (AORD) was selected as the target market. It includes ...
Exact critical points for testing subhypotheses in nonreplicated three-way experiments

Bandara, E.R.A.D.; Wickremasinghe, W.N. (2008)

In the absence of replication, conventional analyses do not provide ways to examine three-way interaction in threeway experiments. Tucker3 analysis based on alternating least squares algorithm is a general approach that ...
Incorporating intermediate binary responses into interim analyses of clinical trials: a comparison of four methods

Whitehead, A.; Sooriyarachchi, M.R.; Whitehead, J.; Bolland, K.M. (Wiley, 2008)

In clinical trials with a long period of time between randomization and the primary assessment of the patient, the same assessments are often undertaken at intermediate times. When an interim analysis is conducted, in ...
A novel method for testing goodness of fit of a proportional odds model : an application to an AIDS study

Abeysekera, W.W.M.; Sooriyarachchi, M.R. (2008)

Ordinal categorical responses occur commonly in real world situations and many authors discuss the advantages of this type of response. Generalized logit models are popular for analyzing ordinal categorical responses. ...
Fitting correlation adjusted generalized linear models to clustered dengue data measured over time

Perera, H.L.C.; Sooriyarachchi, M.R. (IASSL, 2008)

In this paper the authors address the issue of fitting generalized linear models (GLM’s) in the presence of correlated observations, particularly when the data is clustered. In the usual GLM the responses obtained on each ...
Prognostic models with competing risks : Methods and Application to Prostate Cancer data

Jayawardene, N.K.P.S; Sooriyarachchi, M.R. (IASSL, 2009)

Fundamental statistical methods for analyzing competing risks data have been in discussion for decades. However there’s still an uncertainty on how to approach this type of data due to its complexities and thus there ...
A monte-carlo Simulation study of the properties of Residual Maximum Likelihood (REML) estimators for the linear Gaussian mixed model

Nadaraja, K.; Sooriyarachchi, M.R. (IASSL, 2009)

The linear Gaussian mixed model is a tool box for analyzing experimental as well as non experimental designs in a flexible way elaborately. It is the model that contains mixtures of fixed effects as well as random effects. ...

Now showing items 1-20 of 103

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