Abstract:
In Sri Lanka, leptospirosis is mostly diagnosed on clinical grounds. Serological confirmation is not
obtainable during the acute stage of the illness. There is a need for rapid immunodiagnostics for
confirmation of leptospirosis. Two immunodiagnostic assays, ie enzyme linked immnnosorbent
assay (ELISA) and immunochromatographic technique-Leptocheck-WB test (LCT) are used to
detect leptospira specific IgM antibodies which are prevalent in the early stages of acute infections.