• Development of a Fluoride Riboswitch-based Whole-cell Biosensor for Detecting Fluoride in Drinking Water 

  Kaushalya, K.A.D.; Ariyaratne, W.M.R.; Silva, G.N. (University of Colombo, 2024)

  Drinking water is the main dietary source of fluoride for humans. Despite the benefits, high ingestion of fluoride causes adverse health concerns. Interference with other ions is a major drawback associated with conventional ...
• Fabrication of a Chitosan/Alginate/Ti02 Based Carrier System for the Encapsulation of Gibberellic Acid and Investigating their Release Profiles 

  Arachchi, D.N.A.; De Silva, R.M.; De Silva, K.M.N. (University of Colombo, 2024)

  This work aims the development of a novel chitosan /alginate based carrier system namely, chitosan/alginate/nanoTiO2 (CS /AL/Ti02) for the encapsulation of Gibberellic Acid (GAS, a plant growth regulator, and the investigation ...
• Synthesis of Alpha-pinene Peroxide from Alpha-pinene Using Singlet Oxygen 

  Jayasekara, K.H.L.T.; Abeytunga, D.T.U. (University of Colombo, 2024)

  Alpha-pinene is a naturally occurring monoterpene found in the essential oils of many plants, and its oxidation using singlet oxygen produces alpha-pinene hydroperoxide and hydroxide, compounds with potential biological ...
• Preparation and Characterization of Solid Lipid Nanoparticles Loaded with Ceylon Citronella Oil as a Potent System for Slow-releasing Mosquito Repellent 

  Lokuge, C.M.; De Silva, H.I.C.; Weeratunge, H.D.; Premakumara, G.A.S. (University of Colombo, 2024)

  Ceylon Citronella oil (CCO) is known to possess mosquito-repellent activity The effecdve use of CCO is limited by its hydrophobic and high volatility profile. This research study focused on developing solid lipid nanoparticles ...
• Optimized PEI Mediated Reverse Transfection Methodology for Transient Transfection of HEK293 Cells 

  Sirisena, K.; Wijesinghe, K.J. (University of Colombo, 2024)

  Non-viral vectors are increasingly used for gene delivery due to their safety and flexibility. Polyethyleneimine (PEI) is widely applied in transfection, but high PEI and DNA concentrations can induce cytotoxicity, ...

• Development of a Fluoride Riboswitch-based Whole-cell Biosensor for Detecting Fluoride in Drinking Water 

  Kaushalya, K.A.D.; Ariyaratne, W.M.R.; Silva, G.N. (University of Colombo, 2024)

  Drinking water is the main dietary source of fluoride for humans. Despite the benefits, high ingestion of fluoride causes adverse health concerns. Interference with other ions is a major drawback associated with conventional ...
• Fabrication of a Chitosan/Alginate/Ti02 Based Carrier System for the Encapsulation of Gibberellic Acid and Investigating their Release Profiles 

  Arachchi, D.N.A.; De Silva, R.M.; De Silva, K.M.N. (University of Colombo, 2024)

  This work aims the development of a novel chitosan /alginate based carrier system namely, chitosan/alginate/nanoTiO2 (CS /AL/Ti02) for the encapsulation of Gibberellic Acid (GAS, a plant growth regulator, and the investigation ...
• Synthesis of Alpha-pinene Peroxide from Alpha-pinene Using Singlet Oxygen 

  Jayasekara, K.H.L.T.; Abeytunga, D.T.U. (University of Colombo, 2024)

  Alpha-pinene is a naturally occurring monoterpene found in the essential oils of many plants, and its oxidation using singlet oxygen produces alpha-pinene hydroperoxide and hydroxide, compounds with potential biological ...
• Preparation and Characterization of Solid Lipid Nanoparticles Loaded with Ceylon Citronella Oil as a Potent System for Slow-releasing Mosquito Repellent 

  Lokuge, C.M.; De Silva, H.I.C.; Weeratunge, H.D.; Premakumara, G.A.S. (University of Colombo, 2024)

  Ceylon Citronella oil (CCO) is known to possess mosquito-repellent activity The effecdve use of CCO is limited by its hydrophobic and high volatility profile. This research study focused on developing solid lipid nanoparticles ...
• Optimized PEI Mediated Reverse Transfection Methodology for Transient Transfection of HEK293 Cells 

  Sirisena, K.; Wijesinghe, K.J. (University of Colombo, 2024)

  Non-viral vectors are increasingly used for gene delivery due to their safety and flexibility. Polyethyleneimine (PEI) is widely applied in transfection, but high PEI and DNA concentrations can induce cytotoxicity, ...
• Evaluation of Kithul Treacle as a Potential Substrate to Grow Monascus purpureus in Preparation of Monascus-fermented Black Tea 

  Hasara, U.P.S.; Subasinghe, P.; Abewickrama, G.; Hettiarachchi, C.; Kaumal, M.N. (University of Colombo, 2024)

  Monascus purpureus is a valuable fungal strain that produces different bioactive pigments, and it is being used to produce a variety of food products. The secondary metabolites synthesized by purpureus are used as colorants ...
• Fitness Evaluation of Two Component Release of Insects Carrying Dominant Lethality (RIDL) Based Transgenic Aedes aegypti Mosquito Lines 

  Dilani, P.V.D.; Dassanayake, R.S.; Dilruk, H.M.; Hapugoda, M.; Zurita, F.; Hettiarachchi, C.; Gunawardene, Y.I.N.S. (University of Colombo, 2024)

  Transgenic Aedes aeopti mosquito lines are developed for effective dengue control. A two-component RIDL system, with driver and effector transgenes, was previously engineered into the mosquito genome to create two separate ...
• Determination of Antioxidant and Antimicrobial Activities of Different Parts of Leucas zeylanica (Gata Thumba) Plants 

  Fernando, M.S.D.; Hettiarachchi, C. (University of Colombo, 2024)

  Leucas zeylanica is a medicinal plant that contains a variety of antioxidant and antimicrobial compounds and it is widely distributed in Asian and African countries. Although few studies have published the antioxidant and ...
• Designing Surface Enhanced Raman Scattering (SERS) Substrates Using Citrate-capped and Cysteamine-capped Gold Nanoparticles to Modify Glass Substrate and Polystyrene Well Plates 

  Rodrigo, D.; Gunewardene, S.; Jayaweera, H.; Abeyasinghe, N. (University of Colombo, 2024)

  Surface-enhanced Raman scattering (SERS) is a powerful technique for enhancing Raman signals of molecules adsorbed on metallic plasmonic nanostructures such as gold nano particles. This study examines the synthesis and ...
• Low-cost microfluidic electrochemical paper-based device to detect glucose 

  Kaumal, M. N.; Jayarathna, H. K. V. S.; Fernando, W. T. H. (University of Kelaniya Sri Lanka, 2022)

  Continuous monitoring of the level of glucose is essential to maintain the health of a diabetic patient. The use of invasive methods to obtain blood samples to detect glucose is the current method, but such methods may not ...
• Molecular dynamics study on the effect of As(III) ion on human uracil DNA glycosylase enzyme 

  Paligaspe, Priyani; Weerasinghe, S.; Dissanayake, D. P.; Senthilnithy, R. (University of Colombo, 2021)

  Mutations in DNA occur due to exposure to chemicals, toxins, and radiation. The presence of uracil in DNA is a modification that occurs due to the misincorporation and spontaneous deamination of cytosine. Glycosylases ...
• In-silico investigation to predict the potential of HDAC inhibitors to inhibit the HDLP enzyme: A molecular dynamics study 

  Dushanan, R.; Weerasinghe, S.; Dissanayake, D. P.; Senthilnithy, R. (University of Colombo, 2021)

  Histone deacetylase (HDACs) enzyme plays an important role in regulating gene expression, thus could be considered as an effective target for cancer treatment. HDAC inhibitors are the new and promising class of drugs ...
• Application of thermally derived merino wool carbon quantum dots for the detection Hg2+ in aqueous medium 

  Tissera, N.D.; Wijesena, R.N.; de Silva, Rohini M.; de Silva, K.M. Nalin (University of Colombo, 2020)

  A facile, simple and low-cost approach for synthesizing highly fluorescent carbon quantum dots (CQDs) is reported. Wool consists of amino acids linked together by peptide linkages is abundant in C, N, H, O and S. Due to ...
• Application of thermally derived merino wool carbon quantum dots for the detection Hg2+ in aqueous medium 

  Tissera, N.D.; Wijesena, R.N.; de Silva, Rohini M.; de Silva, K.M. Nalin (University of Colombo, 2020)

  A facile, simple and low-cost approach for synthesizing highly fluorescent carbon quantum dots (CQDs) is reported. Wool consists of amino acids linked together by peptide linkages is abundant in C, N, H, O and S. Due to ...
• Improving the moisture management properties of cotton fabrics with chitin nanofibers 

  Wijesena, R.N.; Tissera, N.D.; de Silva, Rohini M.; de Silva, K.M. Nalin (University of Colombo, 2020)

  Effective moisture management of fabric will depend mainly on its ability to transport moisture away from the inner side of the fabric to the outer surface where more spreading and evaporation occurs. This will significantly ...
• Comparative analysis of Kajjali (1:1) in Ayurveda Rasashastra with synthesized β-HgS 

  Gunaratna, T.A.N.R.; de Silva, Rohini M.; Prajapati, P.K.; de Silva, K.M. Nalin (University of Colombo, 2020)

  The black colour compound prepared manually by grinding purified mercury and purified sulphur is known as kajjali in Ayurveda rasashastra. This insoluble inorganic compound is known as β-HgS in chemistry. Although kajjali ...
• Synthesis of MMT-La-Alginate composite for water purification 

  Wimalasiri, A. K. D. V. K.; Fernando, M.S.; Gayashan, M.K.; de Silva, Rohini.M.; de Silva, K.M. Nalin; Dissanayake, D.P (University of Colombo, 2020)

  In this study, MMT-La-Alginate (MMT-La-ALG) composite was synthesized, characterized, and analyzed for its fluoride adsorption capacity and antibacterial properties. The composite was synthesized using MMT, lanthanum ...
• Multifunctional HAP nanocomposites for antimicrobial activity 

  Fernando, M.S.; Wimalasiri, A.K.D.V.K.; Gayashan, M.K.; de Silva, Rohini.M.; de Silva, K.M. Nalin; Dissanayake, D.P. (University of Colombo, 2020)

  Contamination of water bodies by chemical and biological pollutants has resulted in shortage of clean and safe drinking water all over the world. Hydroxyapatite based nanocomposites have been identified as promising ...
• In-silico study of binding interaction of a xanthone of Hypericum mysorense with aldose reductase 

  Abdulla, S.M.; Weerasinghe, M.S.S.; Premakumar, G.A.S.; Ranasinghe, P.; Udawatte, C. (University of Colombo, 2020)

  In present, emphasis on plant research has vastly increased worldwide and a large body of evidence has been collected to show the immense potential of medicinal plants used in various traditional systems. Hypericum ...
• Dye removing ability of metal oxide nanoparticles synthesized with plant extracts 

  Liyanage, P.A.M.; Vithanarachchi, S.M. (University of Colombo, 2020)

  Release of untreated effluents from various industries into water bodies is one of the main concerns of environmental pollution. Among many pollutants released into waterways, dyes are one of the major contributors of ...

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