Abstract:
Release of reactive oxygen and reactive nitrogen species (ROS and RNS) contribute to
increased oxidative stress and also tissues damage which is thought to lead to multi-organ failure
in Leptospirosis. The antioxidant capacity (AOC) of serum provides a measure of overall
protection against oxidative damage. RNS (ie., nitric oxide (NO ) released is immediately
converted to NO2 and NO3 (NOx) and serum NOx levels reflect the level of NO released.
