Abstract:
A 58-year-old woman, presented with progressive
androgenization including virilisation, and
hypertension. On clinical examination she had a
Ferriman Gallway score of 10 and clitaromegaly.
Vaginal examination revealed a right adnexal mass
of approximately 4cm diameter. Her total serum
testosterone level was 4.5ng/ml (normal range 0.06-
0.82) and free testosterone level was 16.6 pg/ml
(normal range 0.1- 1.7 and was not suppressed with
dexamethasone. Ultrasound scan and C T scan of
abdomen & pelvis confirmed the presence of a solid
ovarian mass while the adrenal glands were normal.
She had total abdominal hysterectomy, bilateral
salpingo - oophorectomy and infracolic omentectomy.
Histopathological examination revealed a leutinised
thecoma of the right ovary. Postoperatively the
testosterone level returned to normal and the patient
had regression of virilism. Ovarian thecoma is a rare
benign tumor of stromal cell origin, and represents
less than 1% of all ovarian tumors. It occurs most
often in perimenopausal and postmenopausal women.
Typical thecomas are almost always estrogenic; the
luteinized forms are virilizing in about 10% o f cases.
We report a case of a 58-year-old post menopausal
woman with a right ovarian leutinised thecoma with
progressive virilization. Only 35 reported cases were
identified by Search of indexed literature from 1966
- 2007,out of which only one was reported in a post
postmenopausal female.
