Department of Parasitology: Recent submissions

Now showing items 1-20 of 24

Clinical and epidemiological studies on the cutaneous leishmaniasis caused by Leishmania (Leishmania) donovani in Sri Lanka

Siriwardana, H.V.; Thalagala, N.; Karunaweera, N.D. (2010)

Sri Lanka is the newest reported focus of human leishmaniasis within the Indian subcontinent. Over the last 8 years, more than 2000 cases of cutaneous leishmaniasis (CL), apparently caused by Leishmania donovani (a species ...
Anthelmintic prescribing patterns of a sample of general practitioners from selected areas in the colombo district of sri lanka

Gunawardena, G.; Siriwardana, C.; Paranavitane, S.R.; Ismail, M.M.; Fernando, S.D. (2008)

General Practitioners (GPs) provide first contact care of children and pregnant mothers in the community. This study ascertained the prescribing pattern of anthelmintics to children and pregnant women by a sample of GPs ...
Toxoplasma, toxocara and tuberculosis co-infection in a four year old child

Guneratne, R.; Mendis, D.; Bandara, T.; Fernando, S.D. (2011)

BACKGROUND: Tuberculosis. toxocariasis and toxoplasmosis are among the common infectious causes of lymphadenitis in children. Cases of Toxoplasma gondii and Toxocara spp co-infection have been reported. CASE PRESENTATION: ...
The 'hidden' burden of malaria: cognitive impairment following infection

Fernando, S.D.; Rodrigo, C.; Rajapakshe, S. (2010)

BACKGROUND: The burden of post-malaria cognitive impairment is often overlooked. Given the large number of infections occurring worldwide, the magnitude of the problem is likely to be substantial. The objectives of this ...
Drug treatment of scrub typhus

Rajapakse, S.; Rodrigo, C.; Fernando, S.D. (2011)

Scrub typhus is a vector-borne disease caused by the pathogen Orientia tsutsugamushi. We review the published literature for evidence on drug treatment in scrub typhus. Doxycycline has a proven efficacy in several trials ...
Current evidence on the use of antifilarial agents in the management of bancroftian filariasis

Fernando, S.D.; Rodrigo, C.; Rajapakshe, S. (2011)

Many trials have explored the efficacy of individual drugs and drug combinations to treat bancroftian filariasis. This narrative review summarizes the current evidence for drug management of bancroftian filariasis. ...
Chemoprophylaxis in malaria: drugs, evidence of efficacy and costs.

Fernando, S.D.; Rodrigo, C.; Rajapakshe, S. (2011)

This review concentrates on different aspects of malaria chemoprophylaxis, namely drug combinations, resistance, impact of malaria prevention in pregnancy and cost effectiveness. A MEDLINE search was performed for all ...
The health and nutritional status of school children in two rural communities in Sri Lanka

Fernando, S.D.; Paranavitane, S.R.; Rajakaruna, J.; Wickramasinghe, S. (2000)

There is growing evidence of considerable burden of morbidity and mortality due to infectious diseases and undernutrition in school children. This study describes the nutritional status and parasitic infections of school ...
Geo-helminth infections in a rural area of Sri Lanka.

Fernando, S.D.; Goonethilleke, H.; Weerasena, K.H.; Kuruppuarachchi, N.D. (2001)

School children carry the heaviest burden of morbidity due to intestinal helminth infection. The objective of this investigation was to study geo-helminth infections in 349 school children aged 6 to 13 years living in a ...
The clinical and epidemiological features of childhood malaria in a moderately endemic area of Sri Lanka

Fernando, S.D.; Wickramasinghe, A.R. (2002)

This study describes some clinical and epidemiological features of childhood malaria in a moderately endemic area of southern Sri Lanka. Six hundred and sixty-two children, who experienced 1,138 attacks of malaria, and 172 ...
The impact of repeated malaria attacks on the school performance of children.

Fernando, S.D.; Gunawardene, D.M.; Bandara, M.R.; De Silva, D.; Carter, R.; Mendis, K.N.; Wickremasinghe, A.R. (2003)

The impact of repeated malarial infections on the school performance of children was investigated in 571 school children 6-14 years of age in a malaria-endemic area in southern Sri Lanka where both Plasmodium falciparum ...
A cost analysis of the use of the rapid, whole-blood, immunochromatographic P.f/P.v assay for the diagnosis of Plasmodium vivax malaria in a rural area of Sri Lanka

Fernando, S.D.; Karunaweera, N.D.; Fernando, W.P.; Attanayake, N.; Wickremasinghe, A.R. (2004)

Between May 2001 and March 2002, a prospective study was conducted in a malaria-endemic area of Sri Lanka, to determine the cost implications of using the immunochromatographic P.f/P.v test to detect Plasmodium vivax ...
Evaluation of a rapid whole blood immunochromatographic assay for the diagnosis of Plasmodium falciparum and Plasmodium vivax malaria.

Fernando, S.D.; Karunaweera, N.D.; Fernando, W.P. (2004)

Microscopic examination of blood smears is the 'gold standard' for malaria diagnosis, but is labour intensive and requires skilled operators. Plasmodium vivax malaria accounts for up to 70% of infections in Sri Lanka. The ...
Community factors affecting long-lasting impregnated mosquito net use for malaria control in Sri Lanka.

Fernando, S.D.; Abeyasinghe, R.R.; Galappaththy, G.N.; Gunawardena, N.; Rajapaksha, L.C. (2008)

The Anti Malaria Campaign distributed approximately 300,000 long-lasting impregnated nets (LLINs) to malaria-endemic areas in Sri Lanka during the years 2005 to 2007. We conducted a community-based cross-sectional survey ...
Sleeping arrangements under long-lasting impregnated mosquito nets: differences during low and high malaria transmission seasons.

Fernando, S.D.; Abeyasinghe, R.R.; Galappaththy, G.N.; Gunawardena, N.; Ranasinghe, A,C,; Rajapaksa, L.C. (2009)

Sleeping arrangements under long-lasting impregnated nets (LLIN) were recorded in 2467 households during the low malaria transmission season (May-June 2007) and the same families were followed up during the high malaria ...
Absence of asymptomatic malaria infections in previously high endemic areas of Sri Lanka

Fernando, S.D.; Abeyasinghe, R.R.; Galappaththy, G.N.; Rajapaksa, L.C. (2009)

As the goal of malaria elimination from Sri Lanka is currently being pursued, this study was planned to determine the prevalence of asymptomatic malaria infections. Five health areas in Trincomalee and Kurunegala districts ...
Candidate gene study of susceptibility to cutaneous leishmaniasis in Sri Lanka.

Samaranayake, T.N.; Fernando, S.D. (2010)

OBJECTIVES: To investigate the association between selected single nucleotide polymorphisms (SNPs) in TNF, LTA and SLC11A1 genes and risk of endemic cutaneous leishmaniasis (CL) in Sri Lanka through a case-control disease ...
Leishmania donovani and Cutaneous Leishmaniasis, Sri Lanka

Yamuna, H.Y.; Siriwardana, D.; Noyes, Harry A.; Beeching, Nicholas J.; Chance, M.L.; Karunaweera, N.D. (2007)

To investigate the relationship of cutaneous leishmaniasis isolates from Sri Lanka to known species, we performed DNA sequencing and microsatellite analyses. We identified Leishmania donovani as the agent of Sri Lanka ...
Leishmania donovani and Cutaneous Leishmaniasis, Sri Lanka

Yamuna, H.Y.; Siriwardana, D.; Noyes, Harry A.; Beeching, Nicholas J.; Chance, M.L.; Karunaweera, N.D. (2007)

Infection with Leishmania protozoa can result in cutaneous, mucocutaneous, or visceral leishmaniasis (VL), depending on the parasite, host, and environmental factors (1). Globally, the disease results in ≈2 million new ...
Clinical and epidemiological studies on the cutaneous leishmaniasis caused by Leishmania (Leishmania) donovani in Sri Lanka

Siriwardana, H.V.Y.D.; Thalagala, N.; Karunaweera, N.D. (2011)

Sri Lanka is the newest reported focus of human leishmaniasis within the Indian subcontinent. Over the last 8 years, more that 2000 cases of cutaneous leishmaniasis (CL), apparently caused by Leishmania donovani (a species ...

Now showing items 1-20 of 24

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