Gastroprotective activity of Ruellia tuberosa root extract in rats

dc.contributor.author	Arambewela, L.S.R.
dc.contributor.author	Thambugala, S R.
dc.contributor.author	Ratnasooriya, W.D.
dc.date.accessioned	2012-03-02T09:38:17Z
dc.date.available	2012-03-02T09:38:17Z
dc.date.issued	2003
dc.identifier.citation	J. Trop. Med. Plants. Vol. 4 No. 2 (Dec 2003)	en_US
dc.identifier.uri	http://archive.cmb.ac.lk:8080/xmlui/handle/70130/2083
dc.description.abstract	Ruellia tuberosa Linn. (Acanthaceae) roots are claimed to possess gastroprotective activity according to some Sri Lankan traditional medical practitioners although this has not been indicated in Ayurveda or folk medicine or confirmed by scientific experimentation. The aim of this study was to evaluate gastroprotective potential of R.tuberosa roots using a crude aqueous extract (470, 940, 1880 mg / kg) and using rat alcohol induced gastric lesion model. Results showed a strong and dose-dependent gastroprotective activity (in terms of reduction in length of haemorrhagic gastric lesions). The extract also had a mild erythropoietic and moderate analgesic activities and was well tolerated even with subchronic treatment. It is concluded that the data provided scientific evidence to support the claim that R.tuberosa root extracts have gastroprotective activity.
dc.language.iso	en	en_US
dc.title	Gastroprotective activity of Ruellia tuberosa root extract in rats	en_US
dc.type	Journal abstract	en_US