Is azathioprine necessary in renal transplantation?

Sheriff, M.H.R.; Yayha, T.; Lee, H.A.

dc.contributor.author	Sheriff, M.H.R.
dc.contributor.author	Yayha, T.
dc.contributor.author	Lee, H.A.
dc.date.accessioned	2012-02-21T03:14:19Z
dc.date.available	2012-02-21T03:14:19Z
dc.date.issued	1978
dc.identifier.citation	Lancet;1978_.pp	en_US
dc.identifier.uri	http://archive.cmb.ac.lk:8080/xmlui/handle/70130/1884
dc.description.abstract	In renal-transplant patients in whom azathioprine therapy was withdrawn early because of bone-marrow suppression no rebound graft rejection was noted. Any subsequent rejection episodes were satisfactorily treated with methylprednisolone pulse therapy. Of 15 patients in whom azathioprine was stopped electively after at least 2 years, only 1 had a subsequent cellular rejection. It is concluded that azathioprine may not have a major role in the immunosuppressive management of renal-transplant patients. If azathioprine has to be stopped there seems to be no good indication for restarting it.
dc.language.iso	en	en_US
dc.title	Is azathioprine necessary in renal transplantation?	en_US
dc.type	Research abstract	en_US