Abstract:
To assess the outcome and complications of pregnancy following
renal transplantation in Sri Lanka. Ten pregnancies following .transplantation
managed between January 1993 and July 1999 by the University Obstetrics and
Gynaecology Unit, De Soysa Hospital for Women, Colombo were reviewed. Five
women had planned pregnancy with an average duration from transplantation to
conception of 2.3 (± 0.2) years; five had an unplanned pregnancy within 12
months of transplantation. All were treated with immunosuppressives, with none
developing rejection. In the planned pregnancy group, 3 developed pregnancy
induced hypertension and 3 impaired glucose tolerance. All delivered mature
healthy babies with an average birth weight of 2.6(±0.3) kg. In the unplanned
group, 1 developed cholestatic jaundice and delivered a growth retarded baby at
36 weeks. Another developed severe pulmonary oedema at 34 weeks (due to a
past myocardial infarction) resulting in a fresh stillbirth. Two others has midtrimester foetal deaths complicating severe diabetes mellitus. The conception at 3
months after transplantation developed diabetes mellitus and pregnancy induced
hypertension, and delivered a live growth retarded baby. None had deterioration
of renal function. Although a successful outcome is possible with stringent prepregnancy selection, maternal morbidity and foetal wastage can be high in those
without
