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Medicine: Recent submissions

  • Diabetes due to the mt3243 A>G mutation among young adult diabetic subjects in Sri Lanka - prevalence and clinical heterogeneity 
    Katulanda, P.; Silva, A.; Mahesh, J. G.; Sheriff, M.H.R.; Matthews, D. R.; McCarthy, M. I.; Gloyn, A. L. (2007)
    The maternally inherited mt3243A>G mutation is associated with a variable clinical phenotype including diabetes and deafness (MIDD). The frequency of this mutation in Sri Lanka (SL) is not known. We aimed to determine the ...
  • Metabolic syndrome among adults in Sri Lanka- urbanization snd sedentary lifestyles driving the epidemic 
    Katulanda, P.; Perera, G. L. R. S.; Karunaratne, K. G. N. S.; Constantine, G. R.; Matthews, D. R.; sheriff, M. H. R. (2007)
    Abstract : Background: Metabolic syndrome has been defined as an entity with clustering of cardiovascular risk factors. There was no countrywide data on metabolic syndrome for Sri Lanka. We aimed to determine the prevalence ...
  • High prevalence of diabetes dyslipidaemia among young adult onset diabetes subjects in Sri Lanka. 
    Katulanda, P.; Silva, A.; Wijeyaratne, S. M.; Shine, B.; Matthews, D. R.; sheriff, M. H. R. (2007)
    Abstract : Objectives: South Asians are at increased risk of diabetes and cardiovascular disease (CVD).We aimed to identify the prevalence and patterns of dyslipidaemias among subjects with young adult diabetes in Sri ...
  • Smoking among adults in Sri Lanka -Facts and figures 
    Wickramasinghe, W. A. K. K.; Karunaratne, K. G. N. S.; Perera, G. L. R. S.; Ganegoda, U. A.; Silva, A.; Katulanda, P.; Constantine, G. R. (2007)
    Abstract : Objectives: To determine the prevalence and patterns of smoking among different socio-demographic groups in Sri Lanka. Methodology: A nationally representative cross sectional study was conducted in 7 out ...
  • Incidence of cough with angiotensin converting enzyme inhibitors in Sri Lankan population 
    Hewamanne, B.S.L.; Constantine, G.R.; Liyanarachchi, T.; Rajapakse, S.; Sheriff, M.H.R. (2000)
    Abstract : Introduction: Angiotensin Converting Enzyme Inhibitors (ACEI) are widely used in clinical practice. Their use is often limited by cough. The incidence of cough among patients taking ACEls varies widely. The ...
  • The use of low molecular weight heparin (LMWH) in haemodialysis (HD) 
    Indrakumar, J.; Mujahieth, M. I.; Rajapakse, S.; Ransi, W.; Premaratne, G. M.; sheriff, M. H. R. (1996)
    Abstract : Introduction: Unfractionated heparin (UFH) which is widely used as an anti coagulant in haemodialysis cannot be regarded as an ideal anticoagulant since its use is associated with increased post HD bleeding ...
  • Prevalence and correlates of hypertension in Sri Lanka 
    Katulanda, P.; De Vas Gunawardena, A. N. P.; Constantine, G. R; Sheriff, M.H.R.; Matthews, D. R. (2009)
    Hypertension is one of the most. prevalent modifiable risk factors of coronary artery disease, stroke and chronic kidney disease. Baseline data of hypertension among Sri Lankans is invaluable for interventions to prevent ...
  • Adverse effects of a modified regime of intravenous desferrioxamine 
    Senanayake, M. P.; De Silva, W. D. J.; Lamabadusuriya, S. P. (Sri Lanka college of pediatricians, 2001)
    The aim of this study was to investigate the side effects to intravenous desferrioxamine in a cohort of thalassaemic patients receiving 100 mg/kg/day of desferrioxamine on 3 consecutive days coinciding with ...
  • A case of diffuse neonatal haemangiomatosis 
    Wickramasinghe, V. P.; Lamabadusuriya, S. P.; P A S S Dayawansa, P. A. S. S. (Sri Lanka college of pediatricians, 2004)
    Haemangiomata are benign vascular tumours occurring during neonatal period. Multiple haemangiomata occur in about 25% of patients with haeman-gioma1. If they occur only in the skin, the entity is termed benign neonatal ...
  • Suitability of selection criteria as a measure of outcome of medical graduates: University of Colombo 
    Mettananda, D. S. G.; Wickramasinghe, V. P.; Kudolugoda Arachchi, J.; Lamabadusuriya, S. P.; Ajanthan, R.; Kottahachchi, D. (Sri Lanka Medical Association, 2006)
    A prime obstacle faced by a medical educator is selecting the right student to be trained as a doctor, and the general consensus is that . this is a Iso the most difficult task. This study was designed to evaluate the ...
  • Necrotising fasciitis 
    Ajanthan, R.; Lamabadusurlya, S. P. (Sri Lanka college of pediatricians, 2000)
    The first documented case of necrotising fasciitis following ß haemolytic streptococcal septicaemia is reported. An 8 year old boy presented with fever, chills and rigors and difficulty in walking. On admission he was ...
  • Profound thrombocytopenia and generalized hyperpigmentation following pyrimethamine use 
    Senanayake, M. P.; Mettananda, D. S. G.; Vidyatilake, Sudharma (Sri Lanka college of pediatricians, 2011)
    Pyrimethamine is an effective anti-parasitic medication with a narrow therapeutic index. We report a child with toxoplasmosis who developed hyperpigmentation and profound thrombocytopenia during a course of treatment ...
  • Derivation of anthropometric cut-off levels for defining cardiovascular disease risk in Sri Lankan adults 
    Katulanda, P.; Jayawardena, M. A. R.; Ganegoda, U. A.; Sheriff, M.H.R.; Matthews, D. R. (2009)
    Abstract : Objectives: Anthropometric cut-offs derived for Caucasians may not be applicable to other populations .such as South Asians with higher CVD risk. To define population specific anthropometric cut-off values to ...
  • XUR as an indicator of abdominal obesity and cardiovascular disease risk 
    Katulanda, P.; Jayawardena, M. A. R.; Ganegoda, U. A.; Sheriff, M.H.R.; Matthews, D. R. (2009)
    Abstract : Objectives: Abdominal obesity has been described as an independent risk factor for cardiovascular disease (CVD). To compare the ratio between the distance from the lower edge of xiphisternum to the centre of ...
  • Association of body height with diabetes, blood pressure and metabolic syndrome among Sri Lankan adults 
    Ranasinghe, P.; Jayawardena, M.A.N.A.A.D.; Ganegoda, U.A.; Constantine, G.R.; Sheriff, M.H.R.; Matthews, D.R.; Katulanda, P. (2009)
    Being tall has been suggested to be associated with better cardio-vascular health and longevity. We aimed to report the relationship of height with diabetes mellitus, blood pressure (BP) and metabolic syndrome (MS) among ...
  • Cardiac ischaemia and left ventricular hypertrophy (LVH) in electrocardiographs (ECGs) and their correlates among Sri Lankan adults 
    Caldera, T.S.K.R.D.; Liyanage, I.K.; Herath, H.R.I.S.; Constantine, G.R.; Sheriff, M.H.R.; Matthews, D.R.; Katulanda, P. (2009)
    Abstract : Objectives: ECG changes and their correlates have not been previously studied among Sri Lankan adults. We aimed to analyse ischaemic changes and LVH and to determine the association between glucose tolerance ...
  • Comparison of apolipoproteins B and A1 in people with versus without metabolic syndrome 
    Katulanda, G.W.; Katulanda, P.; Sheriff, M.H.R.; Matthews, D.R.; Brian, S. (2009)
    Abstract : Introduction: Apolipoproteins B (apoB) and Al (apoAI) are better predictors of cardiovascular disease (CVD) than traditional lipid indices. Metabolic syndrome (MetS) is a constellation of CVD risk factors. Low ...
  • A mediastinal tumour that disappeared and reappeared 
    Senanayake, M. P.; Ajanthan, R.; S P Sumanasena, S. P.; Lamabadusuriya, S. P. (Sri Lanka college of pediatricians, 2003)
    An 11 year old boy developed breathlessness over 12 days and was admitted to the local hospital with facial oedema and engorged neck veins. He had been "less active" and "feeling unwell" for one month. His father had ...
  • How a social worker could alleviate psychosocial problems of families accessing a child development clinic in Colombo 
    Slee, Verity; Senanayake, S. M.; Senanayake, M. P. (Sri Lanka college of pediatricians, 2008)
    Objectives To describe psychosocial issues faced and the services available to children accessing the child development clinic and how a social worker could help extend services provided through the clinic. Design A cross ...
  • Neonatal morbidity following control of maternal diabetes with human insulin 
    Senanayake, M. P.; Gunawardene, M. K. S. (Sri Lanka college of pediatricians, 2000)
    Objectives To assess the clinical, biochemical and echocardiographic findings of infants born to diabetic mothers given human insulin and to compare the impact of pre-gestational and gestational diabetes. Design Prospective ...

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