Abstract:
The purpose of this study was to validate the use of trans-vaginal ultrasonography in the
assessment of endometrial abnormalities in women with postmenopausal vaginal bleeding.
One hundred and twenty three patients with postmenopausal bleeding were subjected to
transvaginal scan to measure the endometrial thickness and to see the endometrialmyometrial interface regularity. Dilatation and curettage was perfomed on all patients.
Histopathological diagnosis was compared with the endometrial thickness found. Cut-off
value of endometrial thickness to diagnose any abnormality, its sensitivity, specificity,
positive and negative predictive value were calculated. Abnormal endometrial
histopathology for the postmenopausal women was found in 51 (41.5 percentage) out of 123
patients. Receiver operating characteristic curve analysis revealed 3mm to be the optimal
endometrial thickness cut-off for diagnosing endometrial abnormalities. Transvaginal scan
is a valid method in the assessment of endometrial abnormalities in women with
postmenopausal bleeding per vagina. Cut-off value of 3mm is the optimal endometrial
thickness for the diagnosis of endometrial pathology.
