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Title: TA-1 Impact of tea and coffee consumption on stroke and Parkinson disease: A Sri Lankan perspective
Authors: Attanayake, M.K.D.K.
Amaratunga, D.
Gamage, R.
Ragunathan, M.K.
Fernando, H.
Liyanage, J.
Kulthunga, A.
Gunasekara, H.
Dissanayake, Lakshman
Suriyakumara, S.V.T.
Udawatte, N. S.
De Silva, K.R.D.
Keywords: stroke PD tea coffee smoking
Issue Date: Sep-2015
Publisher: Federation of Asian-Oceanian Neuroscience Societies
Citation: Attanayake,M.K.D.K.,Amaratunga,D.,Gamage,R.,Ragunathan,M.K.,Fernando,H.,Liyanage,J.,Kulthunga,A., Gunasekara,H.,Dissanayake,L.,Suriyakumara,S.V.T., Udawatte,N.S.,De Silva,K.R.D.,(2015) "TA-1 Impact of tea and coffee consumption on stroke and Parkinson disease: A Sri Lankan perspective", 6th FAONS: Congress & the 11th Biennial Conference of CNS, Wuzhen
Abstract: Introduction: Tea & coffee consumption could potentially reduce the risk of Stroke & Parkinson Disease (PD) due to their antioxidant properties. However cigarette smoking is lead to oxidative stress that may alter the cellular antioxidant defense system. Method: Study population of 1415 individuals; Stroke:n=772; [Stroke in young patients «45 yrs) accounted for 16% (124/772), median age of onset 38Yrs; male 12% (94/124) 37Yrs, female 4% (30/124) 38Yrs; sex ratio of 3.31: 1. Stroke with age~46; male 56% (402/648) & female 34% (246/648) sex ratio of 1.63: 1], PD: n=143; [Male 61% (87/143), female 39%(56/143), median age of onset 57Yrs] & age matched controls: n=500. Tea, coffee & cigarette consumption were assessed by a stranded questionnaire. Results: Stroke with tea consumptlon..aacups/day 63% (490), 2cups/day 23% 434 (177), 1cup/day 9% (70), median age of onset: 62, 59 & 56Yrs respectively. Stroke with coffee drinkers 36% (278), non-drinkers 64% (494), median age of onset: 61 & 62Yrs respectively. Stroke with smoking 27% (211), non- smoking 37% (288), median age of onset: 60 & 61Yrs respectively. PO with tea consumption: ~3cups/day 51 % (73), 2cups/day 36% (51), 1cup/day 12% (17), median age of onset was 57Yrs in all categories. PO with coffee drinkers 41 % (58), non-drinkers 55% (80), median age of onset: 56 & 57Yrs respectively. PO with smoking 29% (42), non- smoking 71 % (101) median age of onset: 57Yrs in both categories. Conclusion: Results suggestive of regular consumption of Ceylon tea is associated with a decreased risk of early onset of Stroke & PO, where coffee consumption plays a protective role towards early onset of PO, study lay steppingstone on developing neuroprotective nutraceuticals based on unique regional natural products.
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