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Title: In vitro thrombolytic activity of Sri Lankan black tea (Camellia sinensis L.)
Authors: Ratnasooriya, W.D.
Fernando, T.S.P.
Madubasliini, P.P.
Issue Date: 2008
Citation: J. Nat. Sci. Foundation Sn Lanka 2008 36 (i)179-181
Abstract: This study examined the thrombolytic potential of black tea [Camellia sinensis (L) O. Kuntze.] in vitro, using Sri Lankan high grown Dust grade No: 1 black tea and goat blood. Different concentrations of tea were made in isotonic saline (2.5, 5, 10 and 20 mg/mL) and added to preclotted blood and the clot lysis activity was determined (in terms of weight and expressed as % of lysis) following 90 minute incubation at 37°C. The results showed that tea induced mild to moderate (121-520%) and significant (p < 0.05) clot lysis activity. This effect was dose-related. However, the clot lytic activity of black tea was markedly lower than streptokinase (0.1 mg/mL). It is concluded that Sri Lankan black tea possesses fast acting mild to moderate thrombolytic activity in vitro when tested on goat blood.
Appears in Collections:Department of Zoology

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