Please use this identifier to cite or link to this item: http://archive.cmb.ac.lk:8080/xmlui/handle/70130/1770
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dc.contributor.authorSheriff, M.H.R.
dc.contributor.authorRajapakse, S.
dc.contributor.authorAngunawela, P.
dc.contributor.authorAbeygunasekera, S.
dc.contributor.authorPriyadarshana, G.D.P.K.
dc.date.accessioned2012-02-10T05:05:47Z
dc.date.available2012-02-10T05:05:47Z
dc.date.issued2001
dc.identifier.citationSri Lanka Medical Association -114th Anniversary Academic Sessions; 2001_.59ppen_US
dc.identifier.urihttp://archive.cmb.ac.lk:8080/xmlui/handle/70130/1770-
dc.description.abstractTo describe the following in patients undergoing renal biopsies in Sri Lankan hospitals; The common indications, associated clinical and laboratory parameters, prevalence of diseases with secondary renal involvement in this population the pattern of biopsy conclusion. Design: A retrospective descriptive study of 252 renal biopsies carried out from January 1998 to September 2000. Method: Data was collected from biopsy request forms and pathologists reports using a pretested data sheet. Results conclusions: The most frequent indications for biopsy were. nephrotic syndrome 133 (54.3%), asymptomatic proteinuria 31 (12.7%). acute nephritis 27 (11%). In the nephrotic category serum creatinine levels were elevated in 55 (45%) patients. The commonest histological diagnoses were. minimal change disease in 58 (43.6%), focal segmental glomerulosclerosis (FSGS) in 20 (15%). In patients presenting with asymptomatic proteinuria 20 (64.5%) had diastolic blood pressure above 90mmHg. 18 (66.6%) serum creatinine levels were elevated. 2 patients (7.4%) with asymptomatic proteinuria had SLE with renal involvement. Acute diffuse proliferative glomerulonephritis was seen in 12 (44.4%), diffuse proliferative glomerulonephritis ,mesangiocapillary glomerulonephritis in 2 (11%) patients each. More males i.e. 14 (77.7%) had presented with rapidly progressive glomerulonephritis; the pathology of the majority of them was crescentic glomerulonephritis 13 (72.3%). In the asymptomatic heamaturia group, 24 hour urinary protein excretion was over 1500 mg/day in 4 (44%) patients. Biopsy was normal In 4 and showea IgA nephropathy in another 4 (36.4%). Mean age for chronic renal failure was 31 years (SD=11.68). The commonest biopsy conclusions were chronic sclerosing lomerulonephritis in 5 (62.5%) patients and chonic tubulointerstitial nephritis in 3 (37.5%) patients. In patients with acute renal failure, 5 (83%) had identifiable secondary causes, snake bite 2 (40%) was the commonest. Commonest pathology was acute tubulointerstitial nephritis seen in 3 (50%) patients. More females, 4 (66.7%), presented with vasculitic syndrome. All had a secondary cause, SLE HSP accounted for a patient each (16.67%). Biopsy showed minimal change disease in 2 patients (33.3%).
dc.language.isoenen_US
dc.titleA retrospective study of 252 renal biopsiesen_US
dc.typeResearch abstracten_US
Appears in Collections:Department of Clinical Medicine

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